The effect of L-carnitine and catechin together with calories restriction on the reduction of body fat and blood lipids

Abstract

Obesity has become a critical health problem worldwide, and it’s associated with other health issues. Weight loss supplement and caloriese restriction from the daily diet can be implemented to help reduce body weight. L-carnitine and catechin can help reduce body weight by upregulating fatty acid metabolism and altering lipid formation. This study was to assess the effect of L-carnitine and catechin together with calories restriction on body weight and lipid profile. 3T3-L1 cell line was used to assess the effect of L-carnitine and catechin on lipid accumulation. For the human study, a total 30 subjects with obesity were recruited and divided into 2 intervention groups, one is calories restriction group and the other one is L-carnitine and catechin together with calories restriction. Result shows that L-carnitine and catechin significantly reduced fat accumulation in the 3T3-L1 cell model. In the human study, L-carnitine and catechin together with calories restriction significantly reduced body weight, and body fat and improved the lipid profile of the subject, and showed better effect than calories restriction only.