Suppressing the oxidation of LDL and DNA strand breakage of bioactives in dehulled and hull fraction of lentils
Hull/seed coat contains various plant cells that are responsible for sustaining the life of seeds in which phenolics perform significant roles in supporting their functions. In the present study, inhibitory activities against the oxidation of LDL and DNA of soluble- and insoluble-bound phenolics in the dehulled and hull fractions of lentils were determined. In addition, their α-glucosidase inhibitory activity was also assessed. The hulls possessed much higher levels of phenolics in both the soluble- and insoluble-bound forms than dehulled grain fractions, and this led to their potent activities in suppressing the oxidation of LDL and DNA and inhibiting α-glucosidase activity. The high bioactivities of hulls might be due to the existence of various types of cells such as palisade and parenchyma cells containing numerous phenolics for sustaining their functions. This study may help in a better understanding of the localization of soluble- and insoluble-bound phenolics in the structure of lentil.