Total phenolic content, free radical scavenging capacity, and anti-cancer activity of silymarin

  • Uyory Choe
  • Monica Whent
  • Yinghua Luo
  • Liangli (Lucy) Yu

Abstract

Milk thistle (Silybum marianum) seeds are a good source of dietary polyphenols. The bioactive component of milk thistle seeds, silymarin, contains flavonolignans including silybin A, silybin B, isosilybin A, isosilybin B, silychristin, isosilychristin, and silydiain along with the flavonol taxifolin. Silymarin is used traditionally as a natural herbal medicine with minimal side effects. Structurally, each silymarin component possesses phenolic hydroxyl groups and thus works as an antioxidant. In addition to free radical scavenging capacities, silymarin’s anti-cancer activities were reported for many different types of cancers including bladder, breast, colon, gastric, kidney, lung, oral, ovarian, prostate, and skin. The current review will discuss silymarin’s chemical components, total phenolic content, free radical scavenging capacities, and anti-cancer activities.

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Published
2020-06-30
How to Cite
Choe, U., Whent, M., Luo, Y., & Yu, L. (Lucy). (2020). Total phenolic content, free radical scavenging capacity, and anti-cancer activity of silymarin. Journal of Food Bioactives, 10. https://doi.org/10.31665/JFB.2020.10226
Section
Review