Journal of Food Bioactives, ISSN 2637-8752 print, 2637-8779 online
Journal website www.isnff-jfb.com

Original Research

Volume 5, March 2019, pages 136-141


Potential benefits of phenolics from pomegranate pulp and peel in Alzheimer’s disease: antioxidant activity and inhibition of acetylcholinesterase

Tables

Table 1. Quantification of phenolic compounds (µg g−1) in extracts of pomegranate peel and pulp using high-performance liquid chromatography (HPLC)
 
PulpPeel
Data represent mean values for each sample ± standard deviation (n = 3). Means followed by different lower case letters within a row show difference between the samples (p < 0.0001). Abbreviations: GAE, gallic acid equivalents; QE, quercetin equivalents.
Phenolic acids
Gallic acid193.0 ± 11.3b1,005 ± 8.23a
p-coumaric6.40 ± 0.24b23.20 ± 1.16a
Ferulic acid13.30 ± 0.84b103.2 ± 1.52a
Flavonoids
Epicatechin18.55 ± 1.42b198.4 ± 11.4a
Rutin8.97 ± 0.69b144.6 ± 4.09a
Hydrolysable tannins
Punicalagin α63.0 ± 2.0b7,500 ± 11.0a
Punicalagin β66.0 ± 4.0b6,241 ± 10.0a
Anthocyanins
Cyanidin-3,5-diglucoside5573 ± 20.8b23,573 ± 20.8a
Delphinidin 3-glucoside9430 ± 10.0b50,640 ± 20.0a
Pelargonidin 3,5-diglucoside870.0 ± 10.0b8,053 ± 25.2a
Cyanidin 3-glucoside756.7 ± 11.5b22,830 ± 10.0a
Pelargonidin 3-glucoside870.0 ± 10.0b8,053 ± 25.2a

 

Table 2. Radical scavenging activity (µmol TE g−1 DW) of pomegranate peel and pulp extracts by HPLC-DAD-ABTS on-line
 
SampleCompound
gallic acidepicatechinpunicalagin αpunicalagin β
Data represent mean values for each sample ± standard deviation (n = 3). Means followed by different lower case letters within a row show difference between the samples (p < 0.0001). Abbreviations are: TE, trolox equivalents; and DW, dry weight of phenolic extract.
Peel860.62 ± 20.24c545.53 ± 23.17d1,129.73 ± 43.90b1,324.98 ± 49.59a
Pulp124.04 ± 3.28c119.59 ± 1.34c140.04 ± 2.33b299.09 ± 0.86a

 

Table 3. Antioxidant activities and reducing power of phenolics of pomegranate pulp and peela
 
DPPH (µmol TE g−1 DW)ORAC (µmol TE g−1 DW)FRAP (µmol Fe2+ g−1 DW)
Data represent mean values for each sample ± standard deviation (n = 3). Means followed by different lower case letters within a column show difference between the samples (p < 0.0001). Abbreviations are: TE, trolox equivalents; and DW, dry weight of sample.
Pulp108.3 ± 5.95b323.8 ± 10.3b2.47 ± 0.12b
Peel2,372 ± 30.5a7,423 ± 180a56.5 ± 5.90a