Journal of Food Bioactives, ISSN 2637-8752 print, 2637-8779 online
Journal website www.isnff-jfb.com

Original Research

Volume 10, June 2020, pages 64-69


Evaluation of the hypo-allergenicity effect of rice and wheat hydrolysates: a double-blind randomized clinical trial

Tables

Table 1. Shows the baseline characteristics of all subjects
 
Rice hydrolysate (RH)Wheat hydrolysate (WH)
All the values are expressed as average ± standard error mean (SEM). *P value (p < 0.05; RH Vs WH) represented a statistically significant.
Sex (M/F)13/275/5
Age (year-Maen)6–72 (32)8–52 (35)
Eosinophil count (mm3)456.04 ± 90.50433.50 ± 120.26*
ECP (µg/L)20.26 ±6.3221.35 ±6.39
Total IgE (IU/mL)383.80 ± 46.47403.54 ± 42.84*

 

Table 2. Shows the overall patient allergic score (based on questionnaires)
 
WeeksRice hydrolysate (RH)Wheat hydrolysate (WH)
All the values are expressed as average ± standard error mean (SEM). P value (p < 0.05; Baseline Vs 2nd week Vs 4th week). Value represented with different alphabetic superscript letters (a, b, c) were deemed as statistically significant. Allergic scale: 0 to 7, not Allergic; 8 to 12, maybe allergic; 12>, confirmed allergic.
Baseline (0 Week)18.81 ± 8.24a21.50 ± 7.96a
2nd Week18.56 ± 8.27a22.13 ± 7.04a
4th Week16.67 ± 8.24b22.48 ± 6.45a

 

Table 3. Shows the blood eosinophil and IgE count
 
ParametersWeeksRice Hydrolysate (RH)Wheat Hydrolysate (WH)
All the values are expressed as average ± standard error mean (SEM). P value (p < 0.05; Baseline Vs 4th week). Value represented with different alphabetic superscript letters (a, b, c) were deemed as statistically significant.
Eosinophil count (mm3)Baseline (0)456.04 ± 19.50a433.50 ± 61.26a
4th Week403.41 ± 12.05b450.50 ± 69.86b
ECP (µg/L)Baseline (0)20.26 ± 6.32a21.35 ±6.39a
4th Week17.43 ± 4.10b20.58 ± 2.04a
Total IgE (IU/mL)Baseline (0)383.80 ± 46.47a403.54 ± 42.84a
4th Week400.10 ± 45.21a421.82 ± 58.14b

 

Table 4. Shows the TNSS frequency and distress score
 
TNSS ExaminationWeeksRice hydrolysate (RH)Wheat hydrolysate (WH)
All the values are expressed as average ± standard error mean (SEM). P value (p < 0.05; Baseline Vs 2nd week Vs 4th week). Value represented with different alphabetic superscript letters (a, ab, b, c) were deemed as statistically significant.
Total Frequency ScoreBaseline (0 Week)23.37 ± 15.65a25.88 ± 16.91a
2nd Week21.96 ± 13.67b25.50 ± 17.86a
4th Week18.44 ± 15.77c24.80 ± 17.93a
Total degree of distress ScoreBaseline (0 Week)18.11 ± 16.50b21.38 ± 12.86b
2nd Week16.89 ± 15.93b21.75 ± 14.01b
4th Week14.41 ± 17.46c20.90 ± 17.88b

 

Table 5. Shows the SCORAD Skin test scale
 
WeeksRice hydrolysate (RH)Wheat hydrolysate (WH)
All the values are expressed as average ± standard error mean (SEM). P value (p < 0.05; Baseline Vs 2nd week Vs 4th week). Value represented with different alphabetic superscript letters (a, ab, b, c) were deemed as statistically significant.
Baseline (0 Week)99.10 ± 15.18a100.59 ± 17.15a
2nd Week95.56 ± 12.20a86.10 ± 7.00b
4th Week96.65 ± 11.75a55.93 ± 6.56c